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Researchers Discover Genetic Cause of Oligodontia


Researchers at University Medical Center (UMC) Utrecht in the Netherlands  have identified a gene that may cause oligodontia, a rare but serious congenital anomaly defined by the absence of six or more permanent teeth.

According to a press release, the discovery of the so-called LPR6 gene makes it possible to diagnose patients more effectively, provide them with better information, and develop customized treatment. The results were published in The American Journal of Human Genetics

Treatment for oligodontia can take years, and patients are often treated by a dentist, oral surgeon, and an orthodontist. Oligodontia affects 14 out of every 10,000 people in Europe, and there are two types - oligodontia as part of a syndrome and oligodontia as an isolated condition.


Photo provided by University Medical Center Utrecht. 


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