Injectable Anesthetics

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Bing Innovations LLC
Carestream Dental
Dentsply Pharmaceutical
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Milestone Scientific Inc.
Onpharma Inc.
Patterson Dental
Pierrel Pharma
Septodont
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Injectable Anesthetics CATEGORY DESCRIPTION

Local anesthetics interrupt the transmission of nerve impulses between the pain source and the brain by blocking the operation of the sodium potential. Amide local anesthetics for dental use include lidocaine, mepivacaine, articaine, prilocaine and bupivacaine, which differ in terms of rate of onset, duration of action, and maximum recommended dosage. The more closely an anesthetic’s equilibrium pH approximates physiologic pH, the more rapid the onset of action will be, with more acidic solutions demonstrating a slower onset of action. Furthermore, the better the anesthetic molecule binds to the protein in the nerve’s sodium channel, the longer the duration of anesthesia will be.

Because local anesthetics are vasodilators that are absorbed into the circulation, they have systemic effects that are related directly to their blood plasma level. For this reason, local anesthetic cartridges contain a vasopressor in addition to the anesthetic agent. Vasoconstrictors (epinephrine and levonordefrin) counteract the vasodilatory action, slowing removal of the anesthetic from the area of the nerve and, therefore, prolonging its action. Also added is sodium chloride to make the anesthetic solution isotonic with the body tissues.

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DENTSPLY Pharmaceutical’s 4% Articadent DENTAL (articaine HCl 4% with epinephrine injection) is ideal for when the clinician requires...
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Generation 2 has been upgraded with a voltage-regulated power supply as well as microfilaments to enhance its pain blocking capabilities....
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Lidocaine hydrochloride (HCl) 2% with epinephrine is a common local anesthetic that provides a numbing effect for various dental...
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Mepivacaine is a local anesthetic used for adult and pediatric dental procedures. Levonordefrin is added as a vasoconstrictor. ...
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Mepivacaine is a local anesthetic used for adult and pediatric dental procedures. Shatter-resistant, Mylar®-wrapped cartridges...
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VibraJect R3 Anesthetic Injection System ITL Dental The VibraJect R3 greatly reduces or eliminates pain associated with anesthetic...
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Lignospan Anesthetic is a local dental anesthetic, made by Septodont Inc., used for infiltration or nerve block. If used for...
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Scandonest 3% Plain, made by Septodont Inc., is a local anesthetic used for infiltration or block nerve. Formula made without a...
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Vivacaine, by Septodont Inc., is an anesthetic that contains bupivacaine hydrochloride and epinephrine, used for infiltration and nerve...
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OraVerse reverses soft tissue anesthesia, reducing the duration of numbness and accelerating the return to normal function. Phentolamine...
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Computer-Controlled Local Anesthetic Delivery System The computer-controlled Wand All Injection System is designed for unparalleled...

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