MI Paste is a highly effective, safe product that can be used to treat a variety of dental conditions and create a healthy oral environment.
GC America’s MI Paste was first introduced in the United States in 2004 and quickly became a favorite with dental professionals worldwide because of its versatility and safety in treating a variety of oral health conditions. The ability of MI Paste to fight demineralization, improve saliva pH, boost fluoride uptake, soothe sensitive surfaces, and help create a healthy oral environment makes the product a perfect fit with the practice of Minimum Intervention (MI) dentistry and its emphasis on prevention.
The success of MI Paste is due in great measure to the long list of conditions it treats:
- Tooth sensitivity and restoring enamel loss after whitening procedures
- Dry mouth caused by medications
- High levels of oral acid from excessive consumption of soft drinks/sports drinks
- Sensitivity from hot and cold, after bleaching or whitening, and after professional cleaning
- Buffering acids produced by bacteria and plaque
- Protection of teeth during orthodontic treatment
- Providing calcium phosphate for patients suffering from erosion, caries, and conditions arising from xerostomia.
MI Paste may also be recommended for patients undergoing radiation and/or chemotherapy and patients with “meth” mouth and/or “Mountain Dew mouth.” In addition, MI Paste is a good complement to saliva testing, which can be done as part of a patient’s routine examination.
The Science Behind MI Paste
Healthy saliva contains the minerals needed for healthy teeth: calcium, phosphorus, and fluoride. Together with salivary proteins, the saliva delivers bioavailable calcium and phosphate to the tooth surface during remineralization. According to GC America, MI Paste supplies calcium and phosphate needed for patients with poor saliva flow, a situation that can be further augmented by elevating the level of fluoride. MI Paste was the first professional product to contain RECALDENT* (CCP-ACP), which uses casein phosphopeptides (CPP), naturally occurring molecules that can bind calcium and phosphate ions in an amorphous form (ACP). The CPP binds to surfaces such as plaque, bacteria, soft tissue, and dentin, providing a reservoir of bioavailable calcium and phosphorus in the saliva and at the surface of the tooth. ACP is released from the CPP complex during oral acidic challenges. Stabilization of ACP by CPP ensures delivery of calcium and phosphate ions into the tooth structure before they precipitate/ crystallize.1-4 To read more about RECALDENT, visit GC America’s web site (www.gcamerica.com), which contains over 140 research studies.
Rapidity of Results
The speed of MI Paste’s effectiveness depends on individual situations and the specific ways the product is used. If used for relief of sensitivity after a simple whitening procedure, relief should be possible within 2 minutes of applying MI Paste. Before or after ultrasonic prophylaxis or root planing, a 5-minute application of MI Paste is effective.
Because RECALDENT™ (CPP-ACP) is made from a natural milk-derived protein, people with (or suspected to have) milk protein allergies should not use this product. MI Paste should not be used on patients with a sensitivity or allergy to benzoate preservatives. RECALDENT™ (CPP-ACP) is milk-derived with lactose content less than 0.01%.
MI Paste Application
Dental professionals apply MI Paste with custom trays or a gloved finger. When used by the patient at home, MI Paste is typically applied after brushing the teeth, both morning and night, by squeezing a pea-sized amount of MI Paste onto a finger and applying it over the surfaces of the teeth. MI Paste should be left on the teeth for at least 3 minutes. For patients who are whitening their teeth, it is applied immediately after each whitening session. MI Paste may be needed more often for patients with dry mouth.
MI Paste is a water-based, sugar-free créme that is applied topically to the tooth surface or the oral cavity. It is available in 40-g tubes in 5 different flavors: mint, strawberry, melon, tutti frutti, and vanilla. For more information, contact GC America Inc. at www.gcamerica.com or the phone number provided below.
In 2007, GC America introduced MI Paste Plus. This version of MI Paste has all of the same features as the original MI Paste, but now it contains 900 ppm of sodium fluoride. It is not recommended for children under 6 years of age. These patients can still use regular MI Paste. MI Paste Plus is the only product that provides the correct bioavailable ratio of 5 parts calcium to 3 parts phosphate to 1 part fluoride, the same ratio found in healthy enamel. —Jackie Syrop
1. Schupbach P, Neeser JR, Golliard M, et al. Incorporation of caseinoglycomacropeptide and caseinophosphopeptide into salivary pellicle inhibits adherence of mutans streptococci. J Dent Res. 1996;75:1779-1788.
2. Reynolds EC. Remineralization of enamel subsurface lesions by casein phosphopeptide-stabilized calcium photsphate solutions. J Dent Res. 1997;76:1587-1595.
3. Rose RK. Effects of an anticariogenic casein phosphopeptide on calcium diffusion in streptococcal model dental plaques. Arch Oral Biol. 2000;45:569-575.
4. GC America. Data on file.
5. Reynolds EC, Cain DJ, Webber FL, et al. Anticariogenicity of tryptic casein- and synthetic- phosphopeptides in the rat. J Dent Res. 1995;74:1272-1279.