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How ACTIVA BioACTIVE-CEMENT Helps Prevent Restoration Failure


Bioactive materials help prevent restoration failure over the long term by addressing the primary reason restorations fail in the first place: degradation of the bonding layer. Bonding agents tend to degrade over time, causing micro-leakage that can lead to secondary decay and restoration failure.

When it comes to cementation, restoration failure usually happens at the margins. Some traditional cements are soluble and wash out over time. The solubility of these cements combined with the degradation of traditional adhesives can result in micro-leakage. Additionally, continuous pH changes within the mouth and biofilm formation at the gaps can adversely affect some cements and break down the remaining tooth structure.

Unlike some traditional dental cements, ACTIVA BioACTIVE-CEMENT from Pulpdent Corporation participates in a dynamic ionic exchange with tooth structure that continuously seals the margins of the restoration.

SEM Analysis of ACTIVA BioACTIVE-CEMENT after 21 Days in Saline

Compared to the no-saline control, scanning electron microscope (SEM) imaging and energy dispersive X-ray spectroscopy (EDS), after 21 days in saline, show a significant increase in calcium and phosphorus ion concentrations and a decrease in carbon and silica ions, indicating that mineral apatite deposits are forming on the surface.

Figure 1. ACTIVA BioACTIVE-CEMENT Control, no saline 3000x

Figure 2. ACTIVA BioACTIVE-CEMENT 21 days in saline 3000x

Source: Surface deposition analysis of bioactive restorative material and cement. Chao W, Perry R, Kugel G. J Dent Res 95 (Spec Iss A): S1313, 2016 (

ACTIVA BioACTIVE-CEMENT can be used for a wide variety of indirect restorations, including zirconia crowns and bridges, lithium disilicate, resin ceramic crowns, PFMs, stainless steel crowns, implant crowns, and post cementation.

For more information about Pulpdent’s ACTIVA BioACTIVE materials, visit


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